If I could give this place no stars, I would. They are supposedly a UPS drop-off site. I went there…read moretoday to drop off a package, and was told that they are not able to print receipts because the software on their UPS computer has needed an update since December. I can't believe that UPS would permit such a situation. The cashier actually expected me to drop off a package without obtaining a receipt. I called UPS and they told me that this is a privately-owned drop-off location, so they can't do anything about it. I hope that they run their drugstore better than they do their UPS business. Needless to say, I didn't drop my package at their establishment.

Overpriced like everything else on the riverwalk but oddly entertaining. I've never actually been…read moreto a touristy CVS, so I can't really complain based on location and the amusement factor. Obviously there's no actual pharmacy here since it's on the river level with no access to street parking. It's not even your standard CVS. Sure, they have the basics like snacks, cosmetics, etc, but what tickled me were the ducky plushies in cowboy and beaver hats. There are also post cards and $20 phone chargers, one of which I needed since I accidentally left mine at the hotel. Would I come here to buy anything otherwise? Probably not, but it was certainly worth checking out. And the cashier was also very nice. She did ask if I have a phone number with CVS (I haven't for several years now. I wonder if they ever actually close those years old inactive accounts). She also allowed me to simply use the reusable bag from the Alamo we already had with us to save the trouble. Oh and an entire aisle dedicated to Texas and San Antonio. It was a fun time. Also, the shelves could probably stand to be wiped down more. Lots of dust. And what's this? No kitty cats to greet me? Now I'm sad. :( I'd come back just to see them, and they're good for keeping rodents away. So for the cat haters out there, bear in mind they're smarter than many give them credit for as they hunt mice and birds to keep the river walk free of infestations.

The younger lady with the red hair was rude. Customer service is definitely at an all-time low. A…read moresimple "Hello, good morning, how are you?" would have gone a long way. Instead, she just looked at me, I told her what I wanted, and that was it. If you're that tired or unhappy to be there, maybe call out. A little kindness and professionalism make a big difference.

We found plenty of souvenirs for friends and family in addition to some medicinal supplies that we…read morewere looking for. There were a few items that were on clearance that made good gifts. There is even wine in the back. The employees were helpful and friendly.

Have you ever been in the middle of flossing when all of a sudden the last string of floss exits…read morethe dispenser and you're left with no floss? That was the horror I experienced during my work trip. "Why didn't I bring backup floss!?!?!?!?!?" Kidding, who brings backup floss, maybe you do, if so, kudos to you. Enter the RiverCenter Drug Store inside the RiverCenter mall. I refused to pay $4.99 for a single pack of my favorite floss from the hotel store, so I headed to the mall to find a lower price and found it at this store for $2.67. Still overpriced than the usual $0.99 I find at Target but cheaper than $4.99 so I was happy. And, no spend limit to use a credit card like the small kiosk inside the mall who said I had to spend at least $4 to pay for my floss with them. The drug store is large with lots of stuff so if you don't feel like walking to the Walgreens or CVS this is a great option. And yes, I just wrote about buying floss for my first 2018 review! :) What a way to start the year!

I got my first real six-string, I bought it here. I'm Canadian, by the way…read more The man said it right. It's sad that not alot of Yelp users come to places like this and give them a review. Just the fancy restaurants and the tourist hotspots which don't really need a review where your review will get lost in a sea of 20,000 others. This place is super cute with a lot of great stuff and fun stuff and I've stopped in here on several occasions when coming to San Antonio, and I'm sure they will come back here on many occasions in the future. And they have the word five in their name so what rating did you think I was going to give them? This store is a dime.

I marvel at the fact that so many stores -- mere spitting distance from one of America's most…read morehistoric places (The Alamo) -- get no love, nor even attention, from Yelpers. Here is a general store across the street from a site with more than 2,500 photos, almost 1,000 reviews (and an inexplicably low 4-star composite rating) and has a paltry EIGHT reviews and 4 photos (which I'm going to double today). Maybe I just love general stores with the amalgam of touristy stuff, toiletries you forgot to bring, and temptations of the sweet and salty kind. They sum it up best with their motto, "Travel necessities. Hometown setting." First, yes, as you would expect, there is PLENTY of Alamo-related stuff. Neither cheap nor chintzy, there are plenty of Alamo t-shirts, cups, magnets, mugs souvenirs, and other ephemera at prices (at least based on my experience) a bit less expensive than at other establishments. An, if you want to show some Texas pride, there's plenty to buy to remind your friends where you're from and what state not to mess with. And yes, it has the feel with the old-time pharmacy catch-alls, from medicines and ointments to phone chargers and travel bags. The convenience of an airport gift shop without the high prices and drab formulaicness. Five and Dime ain't for the cynic. You'll find the kind of cowboy hats you'd find on a sorority girl at a Saturday night party. You'll find the kind of sombreros you have lying around awaiting the moment when your friend passes out drunk and you can place it on his head and Sharpie a Zapata-style mustache on his upper lip. Yes, there's plenty of humor in the Five and Dime collection! In the end, Five and Dime is a great store for both local and tourist alike. Their hometown philosophy can also be found at their other locations: On the San Antonio Riverwalk, on the Landing in Branson, in Old Town San Diego, Market Street in Charleston, Old Town in St. Augustine (FL), Cannery Row in Monterey (CA), River Street in Savannah (GA), and the Historic Plaza in Santa Fe. All great places, and all where I'll be making a stop at the Five and Dime when I do. See you there!

4/1/2026 - Afternoon between 3:30-5 p.m. Calling to check on a prescription, on hold/waiting for 30…read moremin on the line. No answer. Called the store back and clicked on talking to a person, someone answered, but had to transfer me to pharmacy. Transferred and waited on the line -- until it automatically hung up on me. Called back and on hold another 20 minutes. I gave up. No one in pharmacy every answered.

Not a fan of their prices and their pharmacy couldnt use a little help with customer service and…read morewhy is this the only place that can't seem to get rid of the homeless people. I mean theyre right by the door!!!

Decent CVS next to other restaurants and shops in a safe neighborhood! It was very organized and…read morewith great deals and sales. Parking is plenty!!. The employees were nice when we checked out to purchased our items. Got some body wash and candy. Overall, a smooth process!

Awesome customer service at the Pharmacy and Javier at the register!!!…read moreI strongly recommend cvs!

Watched a employee sigh and slam things at any inconvenience, luckily I wasn't serviced by him but…read morehe was extremely rude to any customer that came to his register. Would make remarks and throw the weight of the items they were purchasing into their hands or in their cart. I genuinely felt bad for older customers who needed a bit more time to read the card scanner as he would immediately press the payment button instead of letting them type in their numbers and would say "you had all this time to type in your number" when they were about to press the keypad. He would throw the things in his hands down and groan every time someone came up to the cash register if he was away. It made the atmosphere very uncomfortable. I would just avoid entering altogether if you notice he's at the register.

The only store open on Christmas day! It wasn't to bad at all. When I parked I thought oh darn it…read moremight be crazy in here with the amount of cars parked. To my surprising the store was clean and organized. The lines weren't crazy and they had everything I needed! I recommend this location as they seem to really have it together on a busy day! Parking was limited but there was also a pretty good amount of people at the red boxes.