1. Five and Dime General Store

    1. Five and Dime General Store

    0

    San Antonio, TX

    Five and Dime General Store

    4.4 (8 reviews)
    InexpensiveDrugstores

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    CVS/pharmacy

    CVS/pharmacy

    3.5
    (47 reviews)
    0.1 mi
    $$

    Overpriced like everything else on the riverwalk but oddly entertaining. I've never actually been…read moreto a touristy CVS, so I can't really complain based on location and the amusement factor. Obviously there's no actual pharmacy here since it's on the river level with no access to street parking. It's not even your standard CVS. Sure, they have the basics like snacks, cosmetics, etc, but what tickled me were the ducky plushies in cowboy and beaver hats. There are also post cards and $20 phone chargers, one of which I needed since I accidentally left mine at the hotel. Would I come here to buy anything otherwise? Probably not, but it was certainly worth checking out. And the cashier was also very nice. She did ask if I have a phone number with CVS (I haven't for several years now. I wonder if they ever actually close those years old inactive accounts). She also allowed me to simply use the reusable bag from the Alamo we already had with us to save the trouble. Oh and an entire aisle dedicated to Texas and San Antonio. It was a fun time. Also, the shelves could probably stand to be wiped down more. Lots of dust. And what's this? No kitty cats to greet me? Now I'm sad. :( I'd come back just to see them, and they're good for keeping rodents away. So for the cat haters out there, bear in mind they're smarter than many give them credit for as they hunt mice and birds to keep the river walk free of infestations.

    The younger lady with the red hair was rude. Customer service is definitely at an all-time low. A…read moresimple "Hello, good morning, how are you?" would have gone a long way. Instead, she just looked at me, I told her what I wanted, and that was it. If you're that tired or unhappy to be there, maybe call out. A little kindness and professionalism make a big difference.

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    Riverwalk entrance
    Riverwalk entrance
    Store hours
    Store hours
    CVS/pharmacy

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    CVS Pharmacy

    CVS Pharmacy

    3.4
    (19 reviews)
    0.1 mi
    $$

    Perfect place for a CVS on the riverwalk. Easy access and good hours. Great spot to grab some…read moredrinks, snacks or almost any other items you may need while visiting or just popping in for some emergency needs - ie. Red Bull, cigarettes, alcohol or Band-Aids. Pleasant staff and easy check out with the self-checkout kiosks.

    Don't send your prescriptions here! They don't do them…read more Rather, this CVS is more like a small snack shop located by the Riverwalk. There's another one close by that's even closer to the river that you can only get in by way of the Riverwalk. This CVS only has a streetside entrance. I don't know what the world record is for the smallest CVS pharmacy, but this is definitely one of the smaller ones out there, so you can imagine the lack of variety in their merchandise. It's mostly snacks inside, but you'll find a few other non-food items in the rear of the shop. However, it's not very well-maintained. I came in three times during my stay in San Antonio. One just to browse around, and two to purchase a snack. On my first trip, the store was empty, and I saw two employees working at the front. On my second trip, the store had a handful of customers, but I didn't recognize an employee until he went up to the front minutes later to service a customer. I was looking around for a small snack, but I was kind of disappointed in what they had. Not that I'm comparing this to the Buc-ee's in New Braunfels, but there are a handful of snacks I would remember at other CVS locations that I couldn't find here. So the small snack I was planning to get had to be a little larger than I expected, which meant spending a little more. I got a Cheetos popcorn, which was the last one they had in stock the evening I went. That was the only item I recall that I hadn't seen before at any CVS. There might have been others, but the Cheetos popcorn was the most noticeable to me. However, upon checkout, I noticed some milk cartons lying on a table, not inside a refrigerator. I touched them, and they weren't even cold at all! Such a small store, but nobody realized the milk that's going to go bad real soon or has gone bad already? And speaking of checkout, if not for the two self-checkout stands at the front of the store, you might be waiting a while for an employee to ring you up, especially if they are assisting other customers. I made another visit on my last week here, and I was the only customer in the store at the time. There were two employees, but neither greeted me or offered to help. I wanted to get an ice cream sandwich, but the price tags were missing on a lot of them! I had to use the coupon scanner to find out the price of them. So inefficient and annoying to have to run back and forth just to find out the prices. I used the self-checkout again because I didn't think the employees were in a mood to ring me up. My suspicion was confirmed when one of them simply glanced at me without a word as I walked out the door with zero intention to make a return visit. If you're looking to make a (hopefully) quick stop to pick up a snack, and you happen to be in the immediate vicinity, this CVS will at least be there to answer your call. Otherwise, I would recommend going to some other CVS, like the other one with the Riverwalk entrance.

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    CVS Pharmacy
    CVS Pharmacy
    CVS Pharmacy

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    RiverCenter Drug Store

    RiverCenter Drug Store

    3.7
    (3 reviews)
    0.2 mi
    $

    We found plenty of souvenirs for friends and family in addition to some medicinal supplies that we…read morewere looking for. There were a few items that were on clearance that made good gifts. There is even wine in the back. The employees were helpful and friendly.

    Have you ever been in the middle of flossing when all of a sudden the last string of floss exits…read morethe dispenser and you're left with no floss? That was the horror I experienced during my work trip. "Why didn't I bring backup floss!?!?!?!?!?" Kidding, who brings backup floss, maybe you do, if so, kudos to you. Enter the RiverCenter Drug Store inside the RiverCenter mall. I refused to pay $4.99 for a single pack of my favorite floss from the hotel store, so I headed to the mall to find a lower price and found it at this store for $2.67. Still overpriced than the usual $0.99 I find at Target but cheaper than $4.99 so I was happy. And, no spend limit to use a credit card like the small kiosk inside the mall who said I had to spend at least $4 to pay for my floss with them. The drug store is large with lots of stuff so if you don't feel like walking to the Walgreens or CVS this is a great option. And yes, I just wrote about buying floss for my first 2018 review! :) What a way to start the year!

    Photos
    River Center Drug Store offers a wide variety of snacks, drinks, alcohol, gifts, medications, toiletries, and San Antonio souvenirs.
    River Center Drug Store offers a wide variety of snacks, drinks, alcohol, gifts, medications, toiletries, and San Antonio souvenirs.
    Assorted Candy, Souvenir candy, specialty candy, classic candy bars, Hershey, Snikers, Reese's
    Assorted Candy, Souvenir candy, specialty candy, classic candy bars, Hershey, Snikers, Reese's
    Healthy snack bars

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    Healthy snack bars

    Five and Dime General Store - drugstores - Updated July 2026

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