Saccharomyces Beer Cafe is probably the best all around beer bar in Brisbane. They skew heavily…read morelocal, from breweries featured, and food ingredients, to wine and distilleries. We had this our last stop on our brewery crawl as it's near the main bus depot heading home. It's a gorgeous spot with low ceilings, pleasant lighting, and a great selection of beer. They have beers from around the world and regularly participate in special tappings, but most of what you'll find is from Queensland.
This is in the arts area of the city, with many galleries, restaurants, street art, and bars. There's lots of options here for non-beer drinkers too, plus a robust menu of hearty bar foods. I got a tasting paddle, which I thought were large pours for the price. The bartenders were welcoming and quick to serve.
They have outdoor seating as well, plus open sides in the hotter months. If you're a beer fan and new to the area, this place is a must-visit. They also have a linked beer store to-go, which also has wine and distilled selections.