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    Comfort Inn & Suites - Hannibal

    2.3 (21 reviews)
    ModerateHotels
    Open Open 24 hours

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    MoMo K.

    Nice hotel. Very busy! 8 min drive from the highway but not a big deal. Rooms were clean. Service is great! Breakfast is like any other choice hotel. Only negative is that the cleaning person was blasting music in hallway while cleaning the rooms next door (the entire time!). That was annoying because I was still sleeping.

    Filthy sink drain, accompanied by a hair.

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    4 months ago

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    2 years ago

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    2 years ago

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    2 years ago

    Just okay. And I have traveled the world in the military and been in some crappy places. Breakfast needed help....weak ass coffee.

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    1 year ago

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    9 years ago

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    4 years ago

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    4 years ago

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    3 years ago

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    3 years ago

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    3 years ago

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    4 years ago

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    5 years ago

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    4 years ago

    Very friendly staff. Room was clean and bed comfortable. Breakfast was fresh and hot. Would stay at this hotel again.

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    7 years ago

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    6 years ago

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    8 years ago

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    Stacey H.

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    6 years ago

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    6 years ago

    Great place. Rooms were very clean and beds were very comfortable. Breakfast was really good!! Definitely recommend this place.

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    7 years ago

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    5 years ago

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    Ask the Community - Comfort Inn & Suites - Hannibal

    Holiday Inn Express & Suites Hannibal - Medical Center

    Holiday Inn Express & Suites Hannibal - Medical Center

    (9 reviews)

    I arrived after dark for business and wound thru some backroads before finding my way to the hotel…read more Pleasantly and happily surprised to find this very nice and new hotel right by the hospital. I was greeted warmly, given helpful info by the desk staff person. Several utility contractors appeared to be using the HIE as their home base and were gathered in the lobby swapping stories and relaxing over beverages. The rooms were high end for an HIE and featured a room with the bathroom to be right on entry, a sliding barn door separating the bedroom from the bathroom and noise from the hallway., a chaise lounge, office set up and large screen TV with a king size bed which was very comfortable. The bathroom had a nighttime light feature and a great shower set up with a sliding glass door. I must say as a frequent traveler this hotel beats some of the more pricier places I've stayed. I skipped the free breakfast so can't comment on it. When in Hannibal MO, do your self a favor and stay here, it's well worth the extra 5 minutes you will spend driving back into town to check out Mark Twain stuff or whatever it might be that brings you to Hannibal

    I cannot believe all the good reviews - this place is horrid! It seems like it was thrown together…read morewith spare parts and discounted fittings. We had a room with a king size bed. We had roaches!!! Minimal housekeeping means they don't even come in and take all the trash, they just grab the old towels and bring in clean ones (hopefully - eco could mean they just dried wet ones in the dryers and brought them out for re-use). The floor felt like it had not been cleaned in ages on my bare-feet which were dirty by the time I went to bed after I had only walked on the room's floor! The bed was so tall you had to do gymnastics to get on it. They say they are eco minded so I think they use the grey water idea for one time our toilet water was literally yellow and no one had peed in it, so I guess someone had peed in the shower and it ended up in my toilet. The lid on the toilet was too small so you were constantly sitting on the bowl part as well. Also being eco minded meant instead of soap being sanitarily wrapped in it's own unopened paper and small bottles of shampoo etc, you got opened bottles of not full to almost empty products, all of which numerous other people had used and perhaps done God knows what with it and the pump handles were probably never cleaned. You could not even use the sink for the fixtures were so ill fitting, you had to use a cup to rinse your hands, otherwise you were constantly hitting the underneath crevice of the counter and you just knew it had not been touched by "housekeeping" since the hotel was built. There is no restaurant only a breakfast hallway which is sectioned "off limits" except 6-8am. The laundry room which you had to do yourself smelt like sewage. I didn't even shower for it was unusable, not only did it have no grab bars or anything, you had to turn backwards to reach the products about three feet from the shower head. Someone said this hotel was new - the shower was rusty. So after having to pole vault onto the bed I left unshowered, in dirty clothes for I did not want to use products someone may have goobered in that stank to high heaven, or launder my clothes in a sewer. We had planned to stay two nights but left after the first one. Very over priced and don't believe a word of the good reviews. And I didn't even say a word about all the clashing decor...

    Comfort Inn & Suites - Hannibal - hotels - Updated July 2026

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