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    Santee Seafood Bistro

    4.1 (123 reviews)
    Open 11:30 am - 8:30 pm
    Updated 2 months ago

    Santee Seafood Bistro Photos

    Business Info

    SANTEE SEAFOOD BISTRO ATMOSPHERE

    What's the vibe?
    Moderate noise
    Casual
    Good for kids

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    Recommended Reviews - Santee Seafood Bistro

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    Reviews With Photos

    Bob B.

    Santee, SC is Our favorite stopover place as we travel Florida - North Carolina several times a year: Nice hotels and several good restaurants. If you're in the mood for Seafood, we really like Santee Seafood Bistro - it's a block off of the main thoroughfare on a quiet street. They also have chicken, ribs, pulled port, brisket. The place is cordial, comfortable and welcoming. Wait staff is knowledgeable and friendly. The same goes for the cook who brings out your meal (a nice touch). I'm a beer guy (nice selection), but I think they have wine and mixed drinks too.

    Savory rich catfish stew in tomato broth over rice. Yum!
    Rich S.

    The Santee Seafood Bistro is a real find, especially if you crave catfish! It's a bright little standalone building just a couple of turns off I-95 at exit 96 onto Old Number Six Highway (SC-6), on Bass Dr at the end of Britain St. There's enough parking to the side and around back. There's outdoor seating on the north side, but it was a little chilly for that in Dec (2024). With a counter up front and tables to the left, there's plenty of seating for the size of the place. The hostess was welcoming and attentive, and the other guests were also friendly to us travelers. We came here for the hot fresh crispy fried whole bone-in catfish, and it was perfectly cooked in a simple light cornmeal salt and pepper breading just like we always had growing up. They also make a savory catfish stew in a rich tomato broth over rice. We were so full, but we did save just enough room for their fresh hot cobbler to finish. Get off that wearisome highway and enjoy some good regular comfort food in a bright place with nice people.

    Fried Seafood Platter
    Joshua R.

    If you want good seafood and friendly service you need to come here! We came in from a long day on the road and felt like we arrived home. The staff were very nice and we were able to get seated right away. They have a wide variety of seafood and bbq options. We ordered the fried seafood platter with a side of okra and the shrimp & grits with a side of collard greens. The seafood was very fresh and tasted great! The amount of food you get for the price is just right! Everything was very good and I highly recommend the collard greens!

    Inside

    As an out-of-state visitor, I wasn't sure what to expect, but this place blew me away! The shrimp and grits were pure comfort food--hearty, soulful, and out of this world. Gina, our warm and friendly server, recommended it, and she nailed it. David brought out hush puppies that were hands-down the best I've ever had (and I've tried them everywhere!). You can tell this small gem is all about down-home cooking done with love. Unlike big, cookie-cutter chain restaurants that churn out soulless meals, this place pours heart into every dish. It's clear they care about feeding people, not just making a buck. Can't wait to come back!

    Entrance

    Monique, the owner, is so friendly, and her food is amazing. The service was great, and both the fried and seared fish were delicious. Everything we tried was fantastic. If you're in Santee or the surrounding area, this place is a must-try!

    Menu (1 of 2)
    Courtenay O.

    After reading reviews, we decided to eat dinner here before checking into our cabin. We are so glad we did! We were warmly greeted by a gentleman before entering the restaurant. Once inside, we were directed to a corner table. He brought us our drinks while we read over the menus he gave us. While we were deciding, someone brought us hot, fresh, delicious hush puppies (3 in a basket). We don't usually like hush puppies, but these were awesome! Another young woman took our orders: crab cakes (4 mini) and cheesy grits for me, and shrimp dinner with corn on the cob for Husband. The restaurant was clean, busy, and everyone was friendly. Masks were worn by the staff and customers. Gloves were worn by anyone handling food. Tables were far enough apart for social distancing. We liked the music playing - Motown! Our food came in a good amount of time - hot and tasty. It was served in to go containers so we could take home whatever we could not eat here. This was due to CoVid - cleaner and safer. Our food was so good! We slowly ate everything, savoring every bite. We are so glad we trusted the best reviews and came here!

    Seafood platter fish scallops shrimps tartar sauce and cocktail sauce seasoned well. Good food

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    2 months ago

    Ate dinner here tonight - the food was wonderful and our server Greg was fantastic. He was very attentive.

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    1 year ago

    Great food and service. Definitely will return when back in the area. Our server was very friendly too

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    7 months ago

    Food was greasy and scallops were under cooked. The seafood platter was small for the price and undercooked. The hush puppies were awesome.

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    8 months ago

    The service was very efficient. The food exceptional. Little dive but really good.

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    2 years ago

    Food is decent. Nothing spectacular. The restaurant could use a good cleaning. Service is pleasant.

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    Page 1 of 4

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    Clark's Inn and Restaurant - Very cool gas fireplace logs - looked real!

    Clark's Inn and Restaurant

    3.6(341 reviews)
    0.1 mi
    $$

    Hello, we have been patronizing Clark's for nearly 8 years and compared to many establishments…read morewe've visited throughout our lifetime Clark's has a FEEL none can match. The food is exceptional and has surpassed any expectation regarding cuisine we've experienced in many different restaurants. Regarding staffing, no words can express the sincere professionalism, courtesy, kindness, friendliness, warmth that is received with each and every visit. Namely Danny (irreplaceable), Mark (irreplaceable), Donna (irreplaceable) Melvin (irreplaceable), "Field" (irreplaceable), Jamie (irreplaceable), Olivia (irreplaceable). If we have forgotten anyone, please forgive us but I am POSITIVE they too add a sense of class and elegance to this fine establishment. Our only concern and disappointment is the newly appointed manager by the name of "Lance" who by our personal observation does NOT relate well with the staff and communicates with them in a disrespectful and abrasive manner. He exhibits mannerisms more suitable for a fast-food establishment. In our opinion he is definitely NOT qualified as Clark's material. We considered never re-visiting Clark s restaurant until he was no longer on staff, however staff insisted we return and not let his temperament dampen our experience. For those who frequent Clark's, please continue to patronize this great establishment and enjoy the unique FEEL and AMBIANCE that makes Clark's the beautiful place that it is..... To the owners we wish you blessings and continued success!! And it was a honor and pleasure meeting both Mr. Mrs. Clark in person.

    Just passing through town.... I got a burger w/ cheese to go. It was loaded with lettuce , tomatoe…read more, onion & delicious fries . idk what they put on their fries but they were excellent. I did not ask for bacon , they put a ton of bacon on it. I picked it off . I hope I wasn't charged for that. It was a $25 lunch. It was a big burger & lots of fries. I had the other half the next day. o would recommend this place. The entire menu looked amazing . the service was very good . I called it in & it was ready in 10 minutes.

    Photos
    Clark's Inn and Restaurant - The library

    The library

    Clark's Inn and Restaurant - Ham and Cheese panini

    Ham and Cheese panini

    Clark's Inn and Restaurant - Restaurant entrance

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    Restaurant entrance

    Cracker Barrel Old Country Store - Cracker Barrel, Santee

    Cracker Barrel Old Country Store

    3.0(126 reviews)
    0.3 mi
    $

    We arrived at our hotel late in the evening and there are not many places open past 9pm in the…read morearea. Cracker Barrel was open until 11pm so we walked over. Justin was our server and he actually greeted us outside. We did not wait more than 2 minutes before someone greeted us at the host stand and actually apologized for making us wait! As we were walking to our table, we noticed the fireplace going and it had real wood! It was so cozy! Justin approached us not long after and offered us to order drinks. We ordered waters, wine, and beer. So the last time we dined at Cracker Barrel was almost 11 years ago because we became deathly ill. The last time, I do not believe they served alcohol so we were surprised seeing it on the menu. Our drinks were delivered quickly and Justin offered us to order dinner. Hubs ordered the Country Fried Turkey with mac and cheese and hashbrown casserole. I ordered the Country Vegetable Plate with green beans, coleslaw, mashed potatoes, and hashbrown casserole. Justin came back later and informed us there was only enough hashbrown casserole for one of us so he said I could order a side salad for no extra charge-sweet! Our food arrived not too long after and the salad was massive! Very fresh too! The Hashbrown casserole was good, everything else was okay but not magnificent. When we went to checkout, there were people taking way too long while their f'in kids were causing havoc in the store so we paid by using the QR code on the receipt. Our check was $45, which was pretty decent for 2 meals, 2 beers, and 1 wine. Oh but there were charges for getting apple butter and having a mix of biscuits and cornbread- was not aware of that when ordering. The bathroom was as clean as it could be but definitely needs to be upgraded. Best part of all, we did not get sick! We will be back if we are in the area again.

    They served me the worst bowl of grits I've ever had. They had no taste nor were they creamy. The…read moreservice was good, Betty was attentive and friendly.

    Photos
    Cracker Barrel Old Country Store
    Cracker Barrel Old Country Store
    Cracker Barrel Old Country Store

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    Santee Seafood Bistro - seafood - Updated May 2026

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