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    Pepperoni's Pizza - Med Center

    3.9 (122 reviews)
    InexpensivePizza, Desserts, Salad
    Open • 10:00 am - 10:00 pm
    Updated over 3 months ago

    Order Pepperoni's Pizza - Med Center Takeout or Delivery

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    PEPPERONI'S PIZZA - MED CENTER ATMOSPHERE

    What's the vibe?
    Quiet
    Casual
    Good for kids
    Outdoor seating

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    Outside
    Jando S.

    Chain pizza has its place in the pizza totem pole, which is closer to, if not near the bottom just below utility pizza (#1). Pepperoni's defies this notion slightly, by essentially working it's way to utility status mostly due to consistency and price. They don't pretend to be fancy, knowing full well their pizzas and wings are going to be on the simpler side. Something that strikes me as weird is that their phone number goes to some central spot where orders are related to the individual locations. It's basically a pizza call center and I can envision a number of issues with this. Substitutions and last minute changes would be problematic, while some element of personalized service is lost. I have never seen this place busy. They have plenty of tables and chairs and the space to boot. Staff is always going to be 1-2 folks deep and seem friendly enough but are silently making pies in the back. The pizza itself is not going to win any awards. All things considered, it's solid in a pinch but don't expect anything fancy. The pizzas are reasonably priced and would work well for any party, be it a kiddie event or fóotball watch party. I think their meat combo pizza is the best bet. Classic pepperoni is also a winner and the supreme was no better than a Costco slice. I wouldn't make it a regular spot, but Pepperoni's is a solid option, especially for folks near NRG and Main St. ____________ (#1) Pizza that is merely good enough for the moment.

    Karen 2.

    staff was nice order was ready on time no waiting around. the ingredients are not very authentic but tasty overall still.

    Elicia D.

    We were craving pizza and based on reviews and vicinity chose pepperonis. We were promptly greeted when we entered. It is a well decorated and I love that there is a large menu outside the building for you to take your time deciding on flavors and items. We went the specialty meat pizza and a classic pepperoni with mozerella sticks. The price was what we expected not too high. The wait was not long and the staff was very friendly. It's definitely a nice eat in place but we wanted to eat at home. The pizza was just okay nothing better than any chain Pizza. No exciting flavors sauce was bland. The mozerella sticks lacked flavor over all it was mediocre at best nothing we would rush to try again. Still searching for a good Houston pizza place

    Mercedes S.

    I really like this pizza joint. Always reliable and consistent pizza taste. It's always served hot too! I order pizza to go most of the rime and this place is Easy to order on the phone with employees and fast! I'll be back soon!

    Small Hawaiian pizza
    Kris G.

    I left my apartment with the intention of getting wings but, as I exited the building, a gentleman passed by me and the smell that followed him made me stop in my tracks. His pizza (not his cologne) smelt mouthwateringly delicious. I needed to know where he got that pie from. I ran after him, inquired, and was told Pepperoni's. "Pepperoni's?!" I asked incredulously, firstly because I had never really heard of them and secondly, because once he told me where it was at, I instantly knew where he was talking about. I drive past this restaurant at least twice a day, but had never thought to try their pies. Well, today was going to be THAT day, because I immediately jumped in my car (remember, I was getting wings) and headed to Pepperoni's. Set in the same plaza as Target and Sonic, Pepperoni's sits unassumingly next to a Wells Fargo ATM. Their menu is displayed on the wall and boasts subs, salads, pizzas, calzones, so this place is more than just a pizza spot. I walked in and ordered a small Hawaiian whose toppings included canadian bacon, bacon, and pineapple, (yes people, I love pineapples on my pizza), and can we just pause to reflect on and appreciate the double bacon toppings? Just to solidify my fat kid status, I added cheese to my pie. Cost? Around $10. Time it took to be made - about 15 minutes. This pie was delicious without the frills that other places may offer; it tasted like it was homemade, amazing, and baked with love. Okay, okay, I may be talking it up a lot, but it was a pretty good pie. So much so, I went back and got another pie two days later *hides face* I don't now if I will try their other menu items but they've got me infatuated with their pies. Customer service is hit or miss - my first experience was great, my second was okay - however, still better than a lot of other places. Also, they've offer cauliflower crust pies, so when I decide to eat healthier in 2020, I will still be able to eat their pizza!!! I don't know if you can tell, but I am very excited about this. All in all, a solid spot.

    Pineapple Cheese
    Keely D.

    Do yourself a favor and order pizza from here!!! After a long day of work, all we wanted was to eat pizza in bed and this had to be some of the best pizza we'd ever had!!! Seriously all of us loved it and we were so thankful to have found this spot!! Vegan/Gluten free options for the win!!!

    Yummy margarita pizza  added spinach
    La Dora M.

    So happy I took my friends advice and tried this quick convenience of the location near target. I love the affordable yet delicious pizza and it's close to my home...yesss!

    Chicken Ranchero and Ranch Dressing 16" Large Pizza
    Gia N.

    OMG just order already you won't regret! This is by far some of the BEST pizza I've had it's a TX fav and now it's mines too. I love how they follow directions on the order the delivery drivers are pleasantry's and did I mention the food is AMAZING. I'm a Marcos Girl but I tried them and I don't plan on going back this spot is hands down 10/10 for me give them a try everything was delicious!

    Pepperoni's Special with a Coke.
    Lindsey S.

    The first time I heard of Pepperoni's was a couple years ago, when my now husband came to Houston to interview for graduate school. I talked to him over FaceTime the night before his interview and, being the worrywart that I am, asked if he'd even eaten anything all day. He told me that "there was only one place I could find that would deliver where I am, and it's called Pepperoni's. Take a look at this pizza." He showed me the luscious, cheesy goodness sitting in a box, and I drooled from 700 miles away. He'd ordered their pepperoni pizza, called the "New Yorker" on their menu. He said it was so good that he'd eaten half of a medium size pizza! Well, his interview went well so we moved to Houston, and have been meaning to try out Pepperoni's together since we moved here! A year and a half later, we finally made it to enjoy a relaxed lunch. Service was very friendly and prompt. We decided on the Pepperoni's Special this time. It was SO yummy! Topped with fresh cheese, veggies and meat. We ordered a large, but it was too much. This made for excellent leftovers the next day. Also-this is kind of weird-the Coke I had with the pizza was VERY GOOD. I'm not sure what makes a fountain drink Coke good, or taste better than other places, but whatever it is, they've got it here. I have heard from other reviews on here that delivery can take a while, and my husband confirmed. He said it took 45-60 minutes after the phone call to receive his food. But it is worth the wait, if you're willing to do so. It is very good pizza for a good price. Plenty of parking at this location, with vegan and gluten free options and plenty of seating.

    Medium New Yorker $15.99
    Brittany N.

    ** 3.5 Stars ** Never tried the Montrose location so I was excited to see they branched out to the Med Center. Ordered a medium thin New Yorker which is described as lots of cheese & pepperoni and extra sauce. Well, It was very crispy and did have lots of cheese but not so much sauce. For $15.99, it was underwhelming. The garlic bread on the other hand was very tasty! And for $2.99, the portion is extremely generous and even comes with marinara. Would I try it again? Maybe. Always wanted to try their single slice servings so I would go that route next time. With that being said, still welcome a new pizza joint to the area : )

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    Adina C.

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    5 months ago

    Amazing service! The lady who took our order was so nice and helpful!!!!!!!!!!!!!!!!!!!!!

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    3 years ago

    Their pizza is absolutely the best I have had since I have moved to Houston! Will be my go to pizza place!

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    Adina C.

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    2 years ago

    Our first time to eat here. Great service and yummy pizza at a great price. We enjoyed it and plan to go back.

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    7 years ago

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    10 years ago

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    3 years ago

    The food was fantastic! You may not think much about it based on its location: but it was fantastic!!!

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    Adina C.

    Thanks for the review and we appreciate your business!

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    4 years ago

    Great pizza and lasagna. Will definitely order from the again! Their pepperoni with thin crust is great!

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    6 years ago

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    3 years ago

    The wings are garbage, don't even bother. Their just pre frozen wings warmed up and rolled around in sauce.

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    Page 1 of 4

    Ask the Community - Pepperoni's Pizza - Med Center

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    The Baker's Son by Valerio's - Piaya Ube

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    So my coworker would always bring ube bread for me to work and I finally got her to give up where…read moreshe goes. She told me to go to the bakers son and make sure I go early because they do sale out and people buy in bulk. I entered with intentions of only getting the ube bread but $40 and 5 items later I went slightly overboard. They have so many items and they all look delicious. The customer service was great and prices were really good. Now to the items, the ube bread is phenomenal, soft, sweet, flavorful 10/10. I also got a biscoff bread sandwich (I'm forget the name) which had the softest and most perfect bread I've ever indulged in. Now to what the employees recommended and the absolute star. The ube Swiss roll. Omg, it was phenomenal. 20 out of 10! It was perfect in every way. I live 30 mins away but will make sure to keep The Bakers Son on a must go place weekly!

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    Pepperoni's Pizza - Med Center - pizza - Updated September 2026

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