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    The Guadalupe on Main

    4.5 (316 reviews)
    ModerateBars, Mexican
    Closed Closed

    The Guadalupe on Main Photos

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    THE GUADALUPE ON MAIN ATMOSPHERE

    What's the vibe?
    Hipster
    Casual
    Classy
    Moderate noise

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    Noah S.

    I just had the best tacos of my life here. The pork belly tacos were so good. I could come back and order 3 separate orders. I know they're just a special menu item, so I'll be keeping my eye out for any time they come back. I also had some wings, and the portion size was great and the sauce was really good, but the breading wasn't for me. I also tried the birria braised short rib, and it was fantastic as well. The meat was so flavorful and the risotto was delicious. The drink menu was pretty great, I had the Disneyland acid trip, and my partner had the smoked old fashioned. Both were tasty and boozy. Finally, our server was super friendly. She had such a positive vibe, it made our meal even better. I can't wait to come back and try more.

    Ngoc H.

    My first time here after a morning at the lake with friends. We arrived there right before it opened and we seated right away. The dining room room was open and airy. The waitress came over and took our order. The food came out piping hot and fresh. We each ordered the Beria tacos with rice and beans. We also ordered the queso corn dip with chips and it was amazing. We ended our meal with tres leches cake and it was good. Overall, I would come here again and try other items.

    Hot sauce-you have to ask for it
    Donnelly N.

    Portions are huge! Came back and tried the chile relleno this time. So delicious. Our server also asked if we wanted to try the hot sauce. Yum! Make sure you ask for it. Lighting levels were lower this time which improved the ambiance.

    Bethany L.

    What a gem of a bar! My husband and I were craving Mexican food and this spot wasn't too far from our hotel. We started with the Cadillac margs and, truly, was probably the best margarita I've ever had. It was perfectly balanced, definitely boozy and not too sweet or strong. We also shared salsa and chips, queso fundido, and some chicken enchiladas in red sauce. All the food was absolutely delicious! We honestly sat at the bar for almost four hours watching a World Cup game and the service was fantastic. We met one of the owners, who was so entertaining. We just really enjoyed our time here and cannot recommend the margs more!

    7'26 - $25 pork belly burrito
    Nonie B.

    This Wednesday lunch was $63.36, without tip. WAY overpriced for an average tasting meal. Albeit it was a pork belly burrito ($25) and fish tacos ($29). And you pay $4.50 for the chips and salsa (receipt attached). And if it wasn't for the salsa to put on the fish tacos, as good as the picture looks, they were over salted and really rather flavorless. This place definitely needs a lunch menu.

    Isabelle T.

    Hidden gem for sure! My friends brought me here and it's a very nice atmosphere. Everything is clean and orderly and the staff were friendly and helpful. They were able to accommodate their veggie burrito into a vegan version. It was a vegetable burrito with a side of rice and beans. It was good! It needs a protein other than beans. A suggestion I have is seasoning some TVP- textured vegetable protein. This is filling, protein rich, and tasty. It's good for vegetarians, vegans and gluten free folk. Another option is tofu. I hear their chef is great, but many chefs aren't familiar with how to properly cook tofu. I was told their chef is now recognized as a top level chef in Arizona. Very cool, but again, let's see some vegan protein added :) They are more of a gluten free type of place. The corn tortillas were SO good!!

    Shrimp ceviche
    Mich B.

    Had late lunch on a Friday afternoon and I'll have to bring friends back! Absolutely delicious Cadillac margarita. Carnitas with poblano rice and refried beans - perfectly seasoned, juicy pork and luscious beans! Also had the shrimp ceviche which was so good, I added a lime squeeze and that just made the flavor burst out. Also handmade corn tortillas rounded out truly spectacular food.

    Denise M.

    We have been here before when this place was Casa Ramos. I guess I expected for them to have made a change, but this place looks exactly the same. It is a very nice looking place with a large fireplace in the center of the wall. Behind the metal cut out screen is going purple lights of the bar. It's kind of a good mix of traditional Mexican and modern decor, leaning more towards modern decor. What I don't like is it feels very echo-y, if that makes any sense. Our server was very nice and very helpful. I ordered one of the specials which was ahi tuna tostadas. There were three of them served on a delicious tostada shell with avocado and black sesame seeds. They were delicious! A friend ordered the street corn which came as a dip with chips. It was really good. I really loved my lunch and the two people with me seem to love theirs. This is a solid choice when you're in Mesa and wanting Mexican food with a bit more upscale atmosphere.

    Chantel Q.

    It was our first time here and they exceeded all of our expectations. Service was a 10/10 the entire time. They check on you, and make sure that you get what you need. It was Friday and we were leaning towards meatless options. My husband had the shrimp fajitas and an old fashioned to drink. He was very happy with his selections. The kids and I had bean and cheese burritos and our youngest had an enchilada. We all enjoyed the chips and salsa. Our daughter and my husband loved the Queso but was a little too thick for me, I really like a creamy queso. Last but not least the vibe and decor of the restaurant is really upbeat and beautiful. I am sure we will be back again, thank you!

    Drink Menu
    Beth S.

    We absolutely loved this restaurant! This was our first visit to The Guadalupe on Main and it was fantastic! From the outside, the building has unique historical restaurant flare. Once you walk inside, the decor is absolutely gorgeous. High ceilings with beautiful light fixtures and perfectly executed decorative touches give this restaurant a warm upscale feeling. The food was absolutely delicious. We started with chips and salsa. They give you green and red salsa. The chips were freshly cooked and the salsa were both delicious! The green one was a touch tangier and spicier than the red, but we enjoyed them both. I had the Birria tacos. The meat was moist and very plentiful inside the tacos. The plate came with two tacos, rice, and beans. Let me just tell you these are not your average rice and beans. They were packed with delicious flavor which left me wanting more. My friend had the fajitas and he said they were spectacular! He ordered the steak fajitas. A heaping portion of meat on top of onions and peppers. The service was impeccable and we even got to meet the owner. He was super nice and very grateful we chose his restaurant for lunch. He also introduced us to their executive chef. You could tell they really had a passion for what they do. This place truly is a hidden gem. With such beautiful decor and delicious food this restaurant is perfect for a date night or just a casual lunch/dinner. Check out my heading inside Video, which immerses you in every inch of this gorgeous restaurant. Thank you once again to the entire staff for a very enjoyable meal.

    Vice & Virtue & classic margarita
    Lenore B.

    My husband and I practically treat this place as our Friday night hangout. We still love grabbing seats at the bar, soaking in the energy, and watching all the action. We've even met another couple here who've since become friends, that's how welcoming and fun the vibe is. On our most recent visit, we tried a couple of new items. First was a starter: shrimp wrapped in bacon, served on a flat skillet with bell peppers, onions, and a lovely chipotle crema. Absolutely fantastic. The flavors were smoky, savory, and perfectly balanced. We also had the chance to try something from their most recent chef's tasting night, a tuna tostada made with sushi-grade tuna. It came as three tostadas topped with beautifully marinated tuna, and it truly tasted like heaven. It probably won't make it onto the regular menu, which makes me even more grateful we got to experience it while we could. Still one of our favorite spots, and we'll definitely be back (as usual!).

    Also, note the vaulted ceiling!
    Dan L.

    First I have to say I just finished lunch at the Guadalupe on main. The second thing I have to say is I am so full. I probably will not eat for a week. That's a lie, it'll probably be more like 3 or 4 hours. So I was stuck in Arizona getting my car fixed so I was kind of trapped at the hotel with limited food options within walking distance. Of course, I opened up Yelp and found that this place called Guadalupe on main was a literal 5-minute walk from the hotel. I was really craving some Mexican food and was super excited about trying this place out. An easy walk down main Street and there it was on the right hand side. The exterior of the building was very modern and elegant, to be honest I thought I was going to have outpriced myself for lunch. But I was pleasantly surprised when I walked through the door The place is just as elegant on the inside, and when I say elegant I don't mean dressy or overly classy, neat and clean, perfect amount of decor, and a very great open seating area. One of the things that stood out was the giant open window at the far side of the restaurant that had a brick wall going up with this beautiful painted mural on it. Not to mention that there was a green alien skeleton relaxing in there. See my pictures if you don't believe me. I ordered some chips and salsa and a beer, and was not disappointed. Sometimes you never know what you're going to get when it comes to chips and salts at a Mexican restaurant. Best case scenario is that they are homemade. Worst case scenario is they bought them from a grocery store down the street. These were fresh and hot and came with two different kinds of salsas... Red and green. This was especially a nice touch as most places only give you the red sauce. For the main course, I ordered carnitas, if you've read any of my other Mexican restaurant reviews on Yelp, you know that that is The benchmark that I judge a Mexican restaurant by. The carnitas was perfectly cooked, had just the right amount of char on it and was moist and flavorful. The rice and beans were top notch and they gave you a little dab of guacamole on the side to put on your tortillas if you wanted to make a taco. I got to meet the owner, Dirty. Mike, super nice guy, very friendly, made great suggestions and you can tell his heart and soul is in this place. Bottom line? If you are ever are in the Mesa area and looking for some good Mexican food, this is a place you need to add to your list. Everything was phenomenal. And I will definitely be going back again!

    Corn Queso and Chips and Salsa
    Rob M.

    We went for dinner on Friday night at 7:30 pm. Call and make reservations in advance --it was busy! The staff was friendly and perhaps a little short as timing ran slightly long. The interior is one large open room and it was loud and just a touch too bright. The menu offers extensive gluten free options. We ordered the corn Queso, Chips and Salsa, Cheese enchiladas with green sauce, chile relleno, Birria tacos, and steak fajitas. The food was delicious! As luck would have it, we were sitting right next to Van Jones! We will be back.

    Azteca salad--no shrimp

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    Quality and taste were ok, however the prices were way too much for what you get. Servings were quite small also.

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    1 month ago

    This place is a 10/10. Amazing food. Super yummy and inventive cocktails. Amazing service.

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    The Guadalupe on Main - bars - Updated September 2026

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