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    Santee Seafood Bistro

    4.1 (130 reviews)
    Closed Closed

    Santee Seafood Bistro Photos

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    SANTEE SEAFOOD BISTRO ATMOSPHERE

    What's the vibe?
    Moderate noise
    Casual
    Good for kids

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    Shrimp and grits
    Mike C.

    Food ! This is real southern cuisine , I got the shrimp and grits with a side of the homemade collards ! Omg best I've ever had . And prices are a deal . Nice scoop of cheese grits topped with a fried green tomato, 8 nice size shrimp and sliced homemade sausage? The gravy was delicious thick brown with just the right heat , collards sweet as candy and the pot liquid wow Ty

    Bob B.

    Santee, SC is Our favorite stopover place as we travel Florida - North Carolina several times a year: Nice hotels and several good restaurants. If you're in the mood for Seafood, we really like Santee Seafood Bistro - it's a block off of the main thoroughfare on a quiet street. They also have chicken, ribs, pulled port, brisket. The place is cordial, comfortable and welcoming. Wait staff is knowledgeable and friendly. The same goes for the cook who brings out your meal (a nice touch). I'm a beer guy (nice selection), but I think they have wine and mixed drinks too.

    Fried Shrimp and Shrimp &Grits

    This was our second time eating here. We had lunch back in 2025 while camping at Santee State Park. We had dinner tonight and it was fabulous! Our waitress Ja was so pleasant and accommodating! Hubby got fried shrimp platter and I had shrimp & grits ( little spicy). It ever in Santee please do yourself a favor and enjoy some fresh seafood!

    Savory rich catfish stew in tomato broth over rice. Yum!
    Rich S.

    The Santee Seafood Bistro is a real find, especially if you crave catfish! It's a bright little standalone building just a couple of turns off I-95 at exit 96 onto Old Number Six Highway (SC-6), on Bass Dr at the end of Britain St. There's enough parking to the side and around back. There's outdoor seating on the north side, but it was a little chilly for that in Dec (2024). With a counter up front and tables to the left, there's plenty of seating for the size of the place. The hostess was welcoming and attentive, and the other guests were also friendly to us travelers. We came here for the hot fresh crispy fried whole bone-in catfish, and it was perfectly cooked in a simple light cornmeal salt and pepper breading just like we always had growing up. They also make a savory catfish stew in a rich tomato broth over rice. We were so full, but we did save just enough room for their fresh hot cobbler to finish. Get off that wearisome highway and enjoy some good regular comfort food in a bright place with nice people.

    Fried Seafood Platter
    Joshua R.

    If you want good seafood and friendly service you need to come here! We came in from a long day on the road and felt like we arrived home. The staff were very nice and we were able to get seated right away. They have a wide variety of seafood and bbq options. We ordered the fried seafood platter with a side of okra and the shrimp & grits with a side of collard greens. The seafood was very fresh and tasted great! The amount of food you get for the price is just right! Everything was very good and I highly recommend the collard greens!

    Inside

    As an out-of-state visitor, I wasn't sure what to expect, but this place blew me away! The shrimp and grits were pure comfort food--hearty, soulful, and out of this world. Gina, our warm and friendly server, recommended it, and she nailed it. David brought out hush puppies that were hands-down the best I've ever had (and I've tried them everywhere!). You can tell this small gem is all about down-home cooking done with love. Unlike big, cookie-cutter chain restaurants that churn out soulless meals, this place pours heart into every dish. It's clear they care about feeding people, not just making a buck. Can't wait to come back!

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    5 years ago

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    4 years ago

    Great food. Great people. Their fried shrimp and hush puppies are awesome. Great place to go and enjoy seafood with the family.

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    4 years ago

    Stopped here for lunch on our way to Savannah...great southern food and wonderful service! Definitely recommend.

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    9 years ago

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    6 years ago

    Food was delicious!!! Service was great!!! I had oyster po boy and my husband had flounder. Music was great too!!

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    Page 3 of 4

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    Clark's Inn and Restaurant - Very cool gas fireplace logs - looked real!

    Clark's Inn and Restaurant

    3.6(344 reviews)
    0.1 mi
    $$

    Hello, we have been patronizing Clark's for nearly 8 years and compared to many establishments…read morewe've visited throughout our lifetime Clark's has a FEEL none can match. The food is exceptional and has surpassed any expectation regarding cuisine we've experienced in many different restaurants. Regarding staffing, no words can express the sincere professionalism, courtesy, kindness, friendliness, warmth that is received with each and every visit. Namely Danny (irreplaceable), Mark (irreplaceable), Donna (irreplaceable) Melvin (irreplaceable), "Field" (irreplaceable), Jamie (irreplaceable), Olivia (irreplaceable). If we have forgotten anyone, please forgive us but I am POSITIVE they too add a sense of class and elegance to this fine establishment. Our only concern and disappointment is the newly appointed manager by the name of "Lance" who by our personal observation does NOT relate well with the staff and communicates with them in a disrespectful and abrasive manner. He exhibits mannerisms more suitable for a fast-food establishment. In our opinion he is definitely NOT qualified as Clark's material. We considered never re-visiting Clark s restaurant until he was no longer on staff, however staff insisted we return and not let his temperament dampen our experience. For those who frequent Clark's, please continue to patronize this great establishment and enjoy the unique FEEL and AMBIANCE that makes Clark's the beautiful place that it is..... To the owners we wish you blessings and continued success!! And it was a honor and pleasure meeting both Mr. Mrs. Clark in person.

    Clark's has been around since I was a small child. Their food is always amazing at a reasonable…read morecost. The service and atmosphere are very pleasant. The staff treat you like family. It's an All-Star set up was excellent service and great taste and food. If you're in our area stop in check out this local restaurant and Inn stay the night stay the week stay however long and enjoy Clarkson and Santee

    Photos
    Clark's Inn and Restaurant - The library

    The library

    Clark's Inn and Restaurant - Ham and Cheese panini

    Ham and Cheese panini

    Clark's Inn and Restaurant - Restaurant entrance

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    Restaurant entrance

    Cracker Barrel Old Country Store - Cracker Barrel, Santee

    Cracker Barrel Old Country Store

    3.0(130 reviews)
    0.3 mi
    $

    food was good. service of food was very good. the…read moreshopping experience was bad. i bought a lot of stuff. after paying and before leaving i foud 2 items i was charged for twice ( 2 seperate items rug up for two instead of one ) i went back to the cashier and showed the reciept. after several miutes of trials a manager was called .... 10 miutes called again .... finially someone came. took one look at the problem and left..... brought out another manager. 10 minutes or more and ok here is your refund. abruptly left....... i asked the cashier to explain the tranaction to me because the amout returned made did not seem to be correct. manager came back. i explained to her why i thought the transaction was in correct. some more trials and oh well here. gave me more money. i asked for a receipt of the whole thing...... i got a receipt that was like my original one no corrections on it. this is a very poorly run establishment. i spent over half an hour trying to get refunded for a mistake they made and truefully did not know how to correct. i would not encourage people to shop here.

    Very happy to stop here since you know what to expect when you walk in. Reasonable prices, clean…read morebathrooms, and interesting things to look at while you wait. We chose to come here on Father's Day because they do call ahead, but it wasn't working that day for some reason which turned into a 30 minute wait for a table for 2. But the food was good as expected and the waitress brought us some extra biscuits and butter for the road when we left.

    Photos
    Cracker Barrel Old Country Store
    Cracker Barrel Old Country Store - Cracker Barrel, Santee

    Cracker Barrel, Santee

    Cracker Barrel Old Country Store

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    Santee Seafood Bistro - seafood - Updated September 2026

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